Neurophysiological and Transcriptomic Predictors of Chronic Low Back Pain: TOWARDS PRECISION PAIN MANAGEMENT

PIs: Dr. Angela Starkweather (UConn) in collaboration with Drs. Cynthia Renn and Susan Dorsey (University of Maryland, Baltimore SON)

Study Coordinator: Bright Eze, UConn SON PhD Candidate

Chronic low back pain (cLBP) is one of the most common and costly pain conditions in the United States, and a leading cause of disability. A majority of cLBP cases are not associated with underlying structural abnormalities, however, accumulating evidence suggests the prolonged, intense sensitivity to pain that characterizes cLBP is caused by distinct changes in expression of immune and other related pain sensitivity genes. The NEAT study aims to discover gene expression biomarkers that predict cLBP so that we may uncover new therapeutic targets, identify patients at risk, and develop early, targeted interventions to reduce disability and improve quality of life for patients

Study website Link

Study Facebook page Link

Self Screening Link

Phone number: 860-486-6930

IRB Number: HP-00088115

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